Host: Taxon infects vertebrates.
Genome: Linear; single stranded; RNA. Genome monopartite. Genomic nucleic acid negative sense; not infectious. Total genome 19000 nucleotides long. Nucleotide sequences of 3'-terminus complementary to similar regions on the 5' end; conserved nucleotide sequences; the same in genera of same family.
Morphology: Virions pleomorphic in shape; filamentous (either branched (sometimes extensively), or simple, circular, 6- or U-shaped,), or spheroidal (and uniform in size after purification by gradient centrifugation). Virions one type of particle only. Virions enveloped; greatly variable up to 1400 nm long, or 790-970 nm long (after purification); about 80 nm in diameter. Surface projections of envelope distinct; spikes (of 7 nm length); dispersed evenly over all the surface (at 10 nm intervals). Nucleocapsids filamentous (tubular); cross-banded; 50 nm in diameter. Symmetry helical. Pitch of helix 5 nm. Nucleocapsid has a dark central axis of 20 nm that appears to be the ribonucleic protein (RNP). The axial channel is about 10-15 nm in diameter.
(Note: for more information about the taxonomy and structure of this virus, see the ICTV database below.)
More Information: | |
Taxonomy: | ICTV Data |
WWW Sites: | All the Virology on the WWW |
Tutorials: | ATV - Filovirus Tutorial |
Filoviridae Images: | ||||
Family | Genus | EM Images | Example Virus Name | Description of Image |
Filoviridae |
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Marburg virus | Marburg virus pictured between two human liver cells at 75,000 x magnification. Electron micrograph courtesy of Dr. F.A. Murphy, UC Davis. |
(Ebola virus Reston) | Electron micrograph of Ebola Reston (Virginia) virus provided by Dr. Art Anderson and modified to include a few monkey images on the viral surface. This image is a "gag", but based on a real image of Ebola-Reston. | |||
Ebola virus Reston | Electron micrograph of Ebola Reston (Virginia) virus provided by Dr. Art Anderson at the US Army Medical Research Institute of Infectious Diseases. This and the following two images are from a paper "Pathology of Experimental Ebola Virus Infection in African Green Monkeys, Involvement of Fibroblastic Reticular Cells." by K. Davis, T. Geisbert and A. Anderson. | |||
Ebola virus Zaire | Ebola virus Zaire Electron micrograph of Ebola Zaire virus taken at the US Army Medical Research Institute of Infectious Diseases | |||
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Ebola virus Zaire | Electron micrograph of Ebola Zaire virus. This is the first photo ever taken,on 10/13/76 by Dr. F.A. Murphy, now at UC Davis, then at CDC. |
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