On 14th May 1796, Jenner vaccinated an 8 year old boy, James Phipps, with material from a cowpox lesion on the hand of a milkmaid, Sarah Nelmes.
James, who had never had smallpox, developed a small lesion at the site of vaccination which healed in 2 weeks.

On 1st July 1796, Jenner challenged the boy by deliberately inoculating him with material from a real case of smallpox !!!

He did not become infected !!!

So that's it then, vaccination was accepted?

© AJC 1997.