Postdoctoral Appointee - Virology
Sandia National Laboratories
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Post Date: May 11, 2017
Job Type: Contract
Degree Requirement: Ph.D.
Years Experience: 1+
Location: US - California - Livermore
Job Reference: 657312
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Description
The Post-Doctoral Appointee Program is designed to recruit outstanding Ph.D. applicants to assist a line organization in meeting its mission objectives and to provide a professional technical work environment for the employee. The Ph.D. must have been conferred within one to five years prior to employment. These assignments are for a one-year period, with the option at management’s discretion to serve no more than five additional one-year assignments.

Sandia/California's Biotechnology and Bioengineering Department is seeking a postdoctoral appointee to join a multidisciplinary team using recent advances in gene editing technology (CRISPR) for genome-wide knockout screening in human cells and for development of novel in vivo CRISPR delivery platforms. We aim to understand the fundamental mechanisms of viral infection of biodefense-related pathogens through these studies with the potential to discover host-directed therapeutic targets. The successful postdoctoral candidate will help develop large-scale gene knockout screening assays to test against multiple virus models, work with an engineering team to develop nanoparticle-based CRISPR delivery vehicles, and transition in vitro findings to animal models. The successful postdoctoral candidate will also be responsible for the effective communication of research results through publications and conference presentations.

Department Description:

Biotechnology and Bioengineering Department, located in Livermore, California and Emeryville, CA, performs biological and bioengineering research with applications in national security, healthcare and alternative energy. We are a diverse research group with a focus on both basic and applied biological research. We seek to address problems with strong ties to national security, such as biodefense and health security, through new research approaches and advanced technology development including microfluidics and nanofluidics. We also seek to develop the science base required by industry to produce clean, efficient, and cost-effective biofuels and other bioproducts on a commercial scale. This work is carried out in partnership with the Department of Energy's Joint BioEnergy Institute (JBEI). Our department is highly multidisciplinary, comprised of researchers with expertise in many disciplines of biology (molecular biology, microbiology, virology, immunology and biochemistry), chemistry (analytical, organic and physical) and engineering (chemical, mechanical and biomedical).

About Sandia:

Sandia National Laboratories is the nation’s premier science and engineering lab for national security and technology innovation, with teams of specialists focused on cutting-edge work in a broad array of areas. Some of the main reasons we love our jobs:

    Challenging work withamazingimpact that contributes to security, peace, and freedom worldwide
    Extraordinary co-workers
    Some of the best tools, equipment, and research facilities in the world
    Career advancement and enrichment opportunities
    Flexible schedules, generous vacations,strongmedical and other benefits, competitive 401k, learning opportunities, relocation assistance and amenities aimed at creating a solid work/life balance*

World-changing technologies. Life-changing careers. Learn more about Sandia at: http://www.sandia.gov

*These benefits vary by job classification.

Skills
Required:

Candidates must have a recent PhD degree in virology, molecular biology, cell biology, immunology, or a related field. The candidate must be a strong individual contributor within a multidisciplinary team comprising engineers, biologists, chemists, and programmers, within the framework of a milestone-driven research project. Strong written and oral communication skills are required. A demonstrated record of high technical achievement (e.g. as evidenced by publication in high-impact scientific journals) and the demonstrated ability to conduct creative, independent research is required.

Desired:

Experience in the following areas is highly desired: Gene editing technology (e.g. CRISPR), high-throughput screening methods, next-gen sequencing, imaging, handling viruses at Biosafety Level 2 (or higher), and animal models of infectious disease.

Notes
Security Clearance:

No clearance required.

This position does not currently require a Department of Energy (DOE)-granted security clearance.

Sandia will conduct a pre-employment background review that includes personal reference checks, law enforcement record checks, and employment and education verifications. Further, employees in New Mexico must pass a U.S. Air Force background screen for access to the work site. Substance abuse or illegal drug use, falsification of information, criminal activity, serious misconduct or other indicators of untrustworthiness can cause access to be denied or terminated, rendering the inability to perform the duties assigned and resulting in termination of employment.

If hired without a clearance, and one subsequently becomes required or you bid on positions that require a DOE-granted security clearance, a pre-processing background review that includes personal reference checks, law enforcement record and credit checks, and employment and education verifications may be conducted prior to a required federal background investigation. Applicants for DOE-granted security clearances must be U.S. citizens and be able to obtain and maintain the appropriate DOE security clearance as required for the position.

EEO Statement:

Equal opportunity employer/Disability/Vet/GLBT


Contact Details
Name: Sandia National Laboratories
Country: United States
URL: http://sandia.jobs/livermore-ca/postdoctoral-appointee-virology/CA3EFDFA0B624E198A995A794D1DCCD3/job/?utm_source=asv&utm_medium=JOBS&utm_campaign=DE-Pilot