Explore novel algorithms for small molecule drug design using artificial intelligence
Develop methods for efficiently improving the quality of cryo-EM structures
Build a structure based pipeline that can process a single protein target – starting from a complete sequence – to discover oral, small molecule drugs that can target a functional site or allosteric site.
Build and validate homology models for targets with no structures
Analyze target druggability based on structure or model
Perform virtual high throughput screening and prioritize top compounds for experimental tests
Guide hit-to-lead and lead optimization
Work closely with medicinal chemists and structural biologists
Interested candidates please e-mail your resume to firstname.lastname@example.org titled “Computational Chemist CHE-CADD-JD No." Primary candidates will be notified by telephone for an interview. Due to time restrictions, other candidates will not be notified. Application materials and additional calls will not be returned.