Applications are invited for a highly motivated postdoctoral Research Associate, funded by a BBSRC award to Dr Trevor Wardill, to develop genome engineering tools for Drosophila and other fly species. You will work in a collaborative multidisciplinary team investigating how visual system neurons process and integrate incoming signals for goal directed behaviours such as finding food or mates while avoiding predation. We use genetics, physiology, behaviour and functional imaging to determine the general principles for visual information processing.
The successful candidate will be directly involved in developing novel genetic labelling methods to help understand the function of visual system neurons in non-model animals. Their aim will be to refine plasmid delivery systems, so that genetically encoded activity reporters can be efficiently expressed in specific neurons of non-model fly species. Experiments will include the development and testing of custom genomic libraries in a variety of plasmid and mobile element vectors. They will help produce molecular tools to benefit the vision research community who use non-model animals, and also have the opportunity to learn visual neuron physiology, including extracellular or intracellular electrophysiological recording and 2-photon imaging.
The ideal candidate will have a PhD in a relevant biological subject, a strong molecular biology background and have previously produced transgenic animals, particularly Drosophila species. They will be able to independently drive the major research focus of developing transgenic animals and molecular tools for vision research (plasmid constructs and protocols).
Location: Department of Physiology, Development and Neuroscience, central Cambridge.
Fixed-term: The funds for this post are available for 2 years in the first instance.