Post Doctoral Scientist - Eli Lilly - Virus:Receptor Interactions
Eli Lilly & Company
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Post Date: Oct 24, 2017
Job Type: Full time
Degree Requirement: Ph.D.
Years Experience: 1+
Start Date: 1st Quarter 2018
Location: US - Indiana - Greenfield
Job Reference: 36095
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The Post Doctoral Scientist is responsible for conducting basic and applied research as an individual contributor in the Elanco Research Labs and the Virology Research group.

The primary research project will involve genetic, molecular, and structural elucidation of virus:receptor engagement. A strong foundation in molecular biology techniques and structural biology will be required to proactively search for solutions in this discovery driven team.

The ability to independently conceptualize and execute experiments, coupled with a “can do” attitude, is essential.

Key Objectives/Deliverables

  • Perform mutagenesis of viral cDNA clones and/or protein expression plasmids. Analyze mutation phenotypes and design follow-up experiments.
  • Design and execute complex protein expression and purification strategies.
  • Analyze oligomeric protein complexes from biochemical and structural perspectives.
  • Participate in cross-functional research teams and effectively collaborate with other functional groups in the organization.
  • Enable the timely progression of research projects through the practical application of scientific expertise which may include planning, protocol creation, hands-on laboratory work.
  • Keep abreast of relevant scientific literature/new technologies /capabilities.
  • Proactively search for novel technologies or product opportunities and establish collaborations and research programs to deliver innovative technical solutions.
  • Demonstrates proficiency at data reporting, interpretation, and trending.
  • Demonstrates good documentation skills with regard to raw data recording and protocol authoring

Ph.D. degree (within last 5 years) in virology, immunology, structural biology, molecular biology or related scientific discipline and/or M.D. or D.V.M.

Research Skills Required

  • Broad knowledge of Virology and Molecular Biology principles including molecular cloning, PCR, Gibson Assembly, and nucleic acid extraction, purification, & sequence analysis
  • Extensive experience with viral reverse genetics including design and rescue of recombinant virus from viral molecular clones / cDNA in cell culture systems.
  • Extensive experience with protein biochemistry, including recombinant protein expression and purification and co-immunoprecipitations
  • Experience or familiarity with structural elucidation of viruses and/or oligomeric protein complexes including crystallography and/or CryoEM
  • Effective oral and written communications skills.
  • personal ethical and quality standards.
  • Exceptional problem solving and decision-making skills.
  • Must be able to work productively in an interdisciplinary team environment

This is an exciting opportunity to experience a research position in an industry setting.

Contact Details
Name: Eli Lilly & Company
Division: Elanco
Department: Virology Research Group